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GLP-1 Weight Loss Medications For Obesity has revolutionized weight loss
GLP-1 (glucagon-like peptide-1) medications are a class of drugs used in the treatment of type 2 diabetes and obesity. They work by mimicking the actions of the natural hormone GLP-1, which is produced in the gut in response to food intake. GLP-1 plays a role in regulating glucose metabolism and appetite.
GLP-1 and the BRAIN play an important role in appetite control and the science of obesity
GLP-1 (glucagon-like peptide-1) weight loss medications are a class of drugs used in the treatment of type 2 diabetes and obesity. They work by mimicking the actions of the natural hormone GLP-1, which is produced in the gut in response to food intake. GLP-1 plays a role in regulating glucose metabolism and appetite.
When GLP-1 medications are administered, they bind to GLP-1 receptors in various tissues, including the brain. In the brain, GLP-1 receptors are located in areas that control appetite and satiety, such as the hypothalamus.
Increased satiety:
GLP-1 medications can promote feelings of fullness and reduce hunger. Activation of GLP-1 receptors in the hypothalamus leads to a decrease in appetite, which can result in reduced food intake.
Regulation of reward pathways:
GLP-1 medications may influence the brain’s reward pathways, which are involved in the perception of pleasure and motivation related to food. By modulating these pathways, GLP-1 medications may reduce the rewarding properties of food and cravings.
WHY people EAT ?
The brain is the master regulator
Homeostatic Eating: driven by hunger
Hedonic Eating: eating for pleasure
Executive Function: deciding to eat
Revolutionary Weight Loss Medications
Proven to have lasting RESULTS
Generic Name: Semaglutide
FDA Approval Year: 2021
BMI Criteria (Obesity): ≥30 kg/m2
Rx Required: Yes
The Good:
- Best in class for weight loss
- Helps you end meals earlier
- Help keeps you full longer
- Weight Loss @1-year = 15%
The Bad
- Nausea is common when starting
- Expensive, may be a high co-payment
- Not all insurances cover it (usually needs MD supervision, detailed diet, exercise and behavior counseling)
Generic Name: Semaglutide
FDA Approval Year: 2021
BMI Criteria (Obesity): ≥30 kg/m2
Rx Required: Yes
The Good:
- Helps you feel full faster
- It can help regulate blood sugar levels and potentially decrease the risk of developing diabetes in overweight or obese individuals
The Bad
- Common side effects Nausea, diaherah is common when starting
- Expensive, may be a high co-payment
- Injectable and not pleasant for those who don’t like shots/needles
Generic Name: Liraglutide
FDA Approval Year: 2014
BMI Criteria (Obesity): ≥30 kg/m2
Rx Required: Yes
The Good:
- Helps you end meals earlier
- Helps keep you full longer
- Weight Loss @1-year = 6%
- Treatment for Type 2 Diabetes
- Good side effect profile
The Bad
- Nausea is common when starting
- Once a day injection
- Expensive, may be a high co-payment
- Not all insurances cover it
- Usually needs MD supervision, detailed diet, exercise and behavior counseling
Generic Name: Phentermine
FDA Approval Year: 1973
BMI Criteria (Obesity): ≥30 kg/m2
Rx Required: Yes
The Good:
- Suppresses Appetite
- Many Doses Available
- Cheap
The Bad
- May develop tolerance and regain weight
- Can increase blood pressure & heart rate
- Not safe for use in some people (Ask MD)
Generic Name: Phentermine + Topiramate
FDA Approval Year: 2012
BMI Criteria (Obesity): ≥30 kg/m2
Rx Required: Yes
The Good:
- Suppresses Appetite
- Combination Therapy
- Weight Loss @1-year = 6-9%
The Bad
- Side Effect: Concentration difficulties
- Side Effect: Memory loss
- Weight Loss @2-year = 7-9%
Generic Name: Bupropion + Naltrexone
FDA Approval Year: 2012
BMI Criteria (Obesity): ≥30 kg/m2
Rx Required: Yes
The Good:
- Suppresses Appetite
- Combination Therapy
- Weight Loss @1-year = 4%
The Bad
- Must not be on Opiates
- Not safe for use in some people (Ask MD)
- No Weight Loss Study >1-year = ???
Frequently Asked Questions
Medical weight loss is a big decision for you and your health. Let us answer all your questions!
What are weight loss medications?
Weight loss medications are prescription drugs that can aid in weight management by suppressing appetite, increasing metabolism, or reducing the absorption of fat. These medications are used in conjunction with a comprehensive weight loss program to support healthy and sustainable weight loss.
How do GLP-1 medications like Ozempic and Sendexa work?
GLP-1 (glucagon-like peptide-1) medications work by mimicking a naturally occurring hormone in the body that regulates appetite and glucose metabolism. These medications can help control hunger, slow down digestion, and regulate blood sugar levels, leading to weight loss.
What is Adipex?
Adipex, also known as phentermine, is a stimulant medication that suppresses appetite. It is used as a short-term treatment for weight loss in individuals with obesity. Adipex works by affecting the central nervous system to reduce hunger and cravings.
What is Qsymia?
Qsymia is a combination medication that contains phentermine and topiramate extended-release. It works by suppressing appetite and enhancing satiety to support weight loss. Qsymia is used as a long-term treatment for obesity when combined with a reduced-calorie diet and increased physical activity.
How does Contrave work?
Contrave is a combination medication that contains bupropion and naltrexone. Bupropion helps reduce appetite and cravings, while naltrexone works by blocking certain receptors in the brain involved in food reward. Contrave is used to support weight loss efforts when combined with a healthy diet and exercise.
Are weight loss medications safe?
Weight loss medications can be safe and effective when prescribed and monitored by a qualified healthcare professional. However, they may have potential side effects and are not suitable for everyone. It’s essential to discuss your medical history, current medications, and any underlying conditions with your healthcare provider before starting any weight loss medication.